Gathering a band of 13, Inspector General Shmada Shinzaemon sets out on a death-defying journey to cut down the shogun’s half-brother, Matsudaira Naritsugu.

In the middle of the 16th century, Hideyoshi, a power hungry warlord sets out to destroy the Momochi clan. He sends his war commander in search of the clan's hidden gold only to find that two daggers are the key to the hiding place of the treasured gold. Spanning decades, the quest for the missing daggers takes Shiranui through war and ancient tradition.

Yataro Tanigawa, a one-eyed hired assassin, impresses yakuza boss Gomyo Kiyoemon with his skill. Gomyo hires Tanigawa as his bodyguard, or yojimbo, to protect him during an inter-clan conflict. Tanigawa quickly rises in stature in the clan, but finds his boss's enemies almost overwhelming.