The first half century of Twentieth Century Fox Film Corporation from its beginnings under Hungarian immigrant William Fox to it emergence as a major studio.

Down-on-his-luck film director Jimmie Dale takes a job at a fly-by-night acting school. He is drawn into the plans of the school's owner to bilk a wealthy young man out of the funds he has supplied to shoot a movie starring pretty student Alice Perkins. But Jimmie hopes to bilk the bilkers by actually completing the movie as ostensibly planned.

After WWI two men go into radio. Failure leads the wife of one to borrow money from another; she goes on, after separation, to stardom. A coast-to-coast radio program is set up to bring everyone back together.

In turn-of-the-century San Francisco, an ambitious vaudevillian takes his quartet from a honky tonk to the big time, while spurning the love of his troupe's star singer for a selfish heiress.

Warner Baxter plays the ambitious producer of a burlesque show who rises to the big time on Broadway. Alice Faye is the loyal burleycue singer who helps make Baxter a success. His head turned by sudden fame, Baxter falls under the spell of a society woman (Mona Barrie) who has theatrical aspirations of her own. She marries Baxter, then convinces him to produce a string of "artistic" plays rather than his extravagant musical revues. The plays are flops, and the woman haughtily divorces Baxter. Faithful Alice Faye, who'd gone to London when her ex-beau was married, returns to the penniless Baxter. She and her burlesque buddies team up to pull Baxter out of his rut and put him on top again.

Reenactments of actual USO experiences of its female stars entertaining troops overseas.

The O'Leary brothers -- honest Jack and roguish Dion -- become powerful figures, and eventually rivals, in Chicago on the eve of its Great Fire.

Inventor Robert Fulton receives support from a tavern owner and a shipyard worker to help realize his dream of a high-powered steamboat.