Jack is now back in the future. He had since lost Lena, and finds out that he's lost his other wife Alice to none other than Harris. While heading out for another assignment, something goes awry with the TCL chamber. Jack finds himself in a whole new dimension. He also runs across a different version of trancers. These guys seem to be in control of this planet. Jack manages to assist a rebel group known as the "Tunnel Rats" crush the rule of the evil Lord Calaban.

Jack Deth is back for one more round with the trancers. Jack must attempt to find his way home from the other-dimensional world of Orpheus, where magic works and the trancers were the ruling class (before Trancers IV, that is). Unfortunately, Jack's quest to find the mystical Tiamond in the Castle of Unrelenting Terror may be thwarted by the return of Caliban, king of the trancers who was thought dead.

After his mission is exposed, an undercover CIA operative stuck deep in hostile territory in Afghanistan must fight his way out, alongside his Afghan translator, to an extraction point in Kandahar, all whilst avoiding elite enemy forces and foreign spies tasked with hunting them down.

New Mexico, present day. Brian and Lukas are off to the desert to join a kegger party and to celebrate Lukas’ victory in a motocross competition. His winning prize includes meeting The Deathinator, the biggest action star in the world. The party gets started under the hot desert sun, but Brian isn’t in the mood, so he wanders off and is soon joined by his friend, Lukas. They discover something strange in the desert which leads them into a secret military laboratory, where they discover the disturbing truth of what the government has been doing. Secret experiments on ants and spiders using DNA found in a meteorite which fell to Earth in 1951 has given birth to mutated giant ants which have overrun the facility. Now, it's up to Brian and Lukas to save the world from a giant ant invasion!