Humans have created a Wall of Severance to separate themselves from the bears, who grew violent and attacked humans after a far-off planet known as Kumalia exploded many years ago, turning into a meteor shower that fell upon earth. Two bears, Ginko Yurishiro and Lulu Yurigasaki, sneak through the Wall of Severance and disguise themselves as humans, enrolling in Arashigaoka Academy and taking an interest in Kureha Tsubaki, a human girl who despises bears.

In the town of Most City, a publishing house resides in the second story of an old building. The staff prints a monthly science magazine about the most shocking phenomena that even scientists find impossible. The handsome editor-in-chief, Taro, is assisted by grade-schooler Jiro and his dog, Saburo. But when scientist Goro Sato seeks their help, it sparks the beginning of a bizarre new tale...