Eddie is a Vietnam veteran who loses his arms and legs when he steps on a land mine, but a brilliant surgeon is able to attach new limbs. Unfortunately, an insanely jealous assistant (who has fallen in love with Eddie's fiancée) switches Eddie's DNA injections, transforming him into a gigantic killer.

In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.