A prostitute aspiring to be an author, a secret satanic sect, and a scientist who has discovered a potion that reanimates the dead intersect in unexpected and comedic ways.

Derek, a handsome young Englishman, begins seducing the local women of a Spanish seaside town, only for a murderer to start picking them off one by one.

A young jazz-composer turns vengeful commando against local drug Mafia Capos when his wife is killed at the hands of Caribbean drug dealers.

William Shatner plays two roles: cowboy Johnny Moon and his ruthless Indian twin brother, Notah. Notah likes peyote and gets the crazy idea that he's the Comanche messiah sent to lead the Comanche nation against the white man but more specifically the dusty desert town of Rio Hondo. Moon, estranged from his brother, decides to stop Notah either by words or by bullets.