A cursed survivor of killings at the Amityville House brings evil to a small island where bizarre genetic experiments are carried out on humans and animals.

A family must put faith in a mysterious priest when an demonic force, connected to a decades-old murders in their home, possesses their daughter.

A young woman and her friends are threatened by an ancient witch's curse when they stop in the town of Amityville to check in on her sickly grandmother.