British documentarian Nick Broomfield creates a follow-up piece to his 1992 documentary of the serial killer Aileen Wuornos, a highway prostitute who was convicted of killing six men in Florida between 1989 and 1990. Interviewing an increasingly mentally unstable Wuornos, Broomfield captures the distorted mind of a murderer whom the state of Florida deems of sound mind — and therefore fit to execute. Throughout the film, Broomfield includes footage of his testimony at Wuornos' trial.

In this documentary, filmmaker Nick Broomfield follows the saga of Aileen Wuornos, a prostitute who has been accused of committing a brutal series of murders. Broomfield conducts interviews with Wuornos herself, and his crew films her trial as well as her interactions with religious fanatic Arlene Pralle, who gives Wuornos dubious advice and legally adopts her. The cameras also roll as the accused's attorney ignores the case at hand to negotiate a deal to sell his client's story.

In 1997, rap superstars Tupac Shakur and Christopher Wallace (aka Biggie Smalls, The Notorious B.I.G.) were gunned down in separate incidents, the apparent victims of hip hop's infamous east-west rivalry. Nick Broomfield's film introduces Russell Poole, an ex-cop with damning evidence that suggests the LAPD deliberately fumbled the case to conceal connections between the police, LA gangs and Death Row Records, the label run by feared rap mogul Marion "Suge" Knight.