Follows the surreal adventures of a cow, named Cow, and her chicken brother, named Chicken. They are often antagonized by "The Red Guy", who poses as various characters to scam them.

Initially debuting as a seven-minute World Premiere Toons pilot, Dexter's Laboratory was expanded into a full series after gaining network approval. The first season, which consists of 13 episodes divided into three segments each, ran on TNT, TBS and Cartoon Network.