Jerranium 90, a "little rock" that made all the papers, is buried deep within the Amazon. And everybody wants it, including crooked importer Handscomb Draile, slimy Gondreau Slykes, cheap crook Carl Traeger and evil scientist Dr. Ellamy Royne.

A small town infestation of crawling alien foreheads that begin attaching to people and taking them over collides with a scientist's experiments to extract foreheadazine and things go horribly horribly wrong.

The men from U.N.C.L.E must stop a band of would-be sorcerers from using a deadly weapon.