Years after a brutal attack left her in a constantly shifting reality, Kirby Mazrachi learns that a recent murder is linked to her assault. She teams with veteran reporter Dan Velazquez to understand her ever-changing present—and confront her past.

Fifty years after the events of Blade Runner 2049, Los Angeles has been reborn, just not by humanity. Cora, a fugitive in a final bid to stop running, takes on one last identity: a Blade Runner. Forced to partner with Olwen, a Replicant days from dying, she hunts down a runaway hiding a truth that could collapse their fragile city.