The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.

On an island somewhere in the Caribbean a professor is experimenting with mankind. Meanwhile, The Red Lips are moonlighting on a striptease world tour, but as soon as they hit the stage, the girls are up to their pasties in stiffs, Satanists and Sapphic sadists, all after the professor's secret formula for human clones!