The lives of three women have a commonality: adoption. Karen is a physical therapist who regrets that, as a teenager, she gave up her daughter for adoption. Elizabeth was an adopted child and is now a successful lawyer, but her personal life lacks warmth. Lucy and her husband have failed to conceive and now hope to adopt a baby to make their family complete.

A fatalistic car crash in Mexico city sets off a chain of events in the lives of three people: a supermodel, a young man wanting to run off with his sister-in-law, and a homeless man.

The most powerful man in the world embarks on a frantic mission to prove he is humanity's savior before the disaster he's unleashed destroys everything.

Captives of the very relationships that define and sustain them, nine women resiliently meet the travails and disappointments of life.