Herbert West is totally out of control on campus, sticking his glowing green reagent into every corpse he can find!

The malevolent inter-dimensional machine is still channeling monsters and blowing minds, but this time things get even more complicated with the arrival of mad med student Herbert West and his dreaded reagent!

Visionary Miskatonic University student Crawford Tillinghast follows in his late father's footsteps and becomes obsessed with completing work on the Resonator, an inter-dimensional device that opens doorways to other worlds.

Detectives are thrust into a chilling hunt for a sadistic serial killer from the past whose return marks the beginning of a new wave of grotesque, otherworldly crimes tied to a cosmic force.