In 1997, a mysterious ghost saved humankind and then disappeared. The mysterious ghost appears again 24 years later and helps a serial killer escape. Kim Sae Ha, Jung Sae Byeok and Song Eo Jin pursue the ghost for different reasons.

Based on a Japanese manga, Kanna-San, Daiseikou Desu, this story revolves around Kang Han-na, an overweight phone sex employee and secret vocalist for Ammy, a famous Korean pop singer who actually lip syncs as she cannot sing. After getting humilitated publicly by an ungrateful Ammy, Han-na undergoes an extreme makeover to become a pop sensation herself.

Heo Im is an oriental doctor, acknowledged as the best in acupuncture and moxibustion in Joseon. His success is blocked due to his low status.