Inspector Nick Cafmeyer seems to have it all - looks, brains and a successful career. But a dark cloud hangs over his life: since the age of nine, he has been haunted by the unsolved disappearance of his younger brother, Bjorn. Plettinckx, a known sex offender, was questioned but quickly released. Plettinckx lives close by and takes fiendish pleasure in harassing Nick. Then, when a disturbing case comes to light involving a missing nine-year-old, Nick heads a massive search which turns into a relentless manhunt.

Vincke and Verstuyft are one of the best detective teams of the Antwerp police force. When they are confronted with the disappearance of a top official and the murder of two prostitutes, the trail leads to the almost retired assassin Angelo Ledda. Since Ledda starts showing symptoms of Alzheimer's, it's getting more and more difficult to complete his contracts. When he has to murder a 12-year old call-girl, he refuses and becomes a target himself. While Vincke and Verstuyft are chasing him and counting the corpses, Ledda is taking care of his employers.

The loss of their young daughter threatens to destroy the love and faith of two married musicians.