John Rambo is released from prison by the government for a top-secret covert mission to the last place on Earth he'd want to return - the jungles of Vietnam.

When former Green Beret John Rambo is harassed by local law enforcement and arrested for vagrancy, he is forced to flee into the mountains and wage an escalating one-man war against his pursuers.

Barney Ross leads a band of highly skilled mercenaries including knife enthusiast Lee Christmas, a martial arts expert Yin Yang, heavy weapons specialist Hale Caesar, demolitionist Toll Road, and a loose-cannon sniper Gunner Jensen. When the group is commissioned by the mysterious Mr. Church to assassinate the dictator of a small South American island, Barney and Lee visit the remote locale to scout out their opposition and discover the true nature of the conflict engulfing the city.