The story of a mysterious woman named Laura, who embarks on a journey to find her true love. The movie's soundtrack is set to four decades of classic rock. Scatman Crothers provides the voice of a living jukebox who narrates the story.

Fritz, now married and a father, is desperate to escape the domestic hell he now finds himself in. Lighting up a joint, he begins to dream about his eight other lives, hoping to find one to provide a pleasant distraction. The drug-induced journeys he takes include spells as an astronaut, Hitler's psychiatrist, a courier travelling in hostile territory during a race war, and as a pupil of an Indian guru in the sewers of New York.

Goofy is a single father raising his son, Max in Spoonerville. As it happens, Goofy and Max end up moving in next door to Goofy's high school friend Pete and his family. Pete's son PJ and Max become best friends practically doing everything together.