Only Koji and the Autobots can save the Earth from the evil Predacons! The Predacons have been battling the Autobots for thousands of years, but this time, they've kidnapped the world's greatest minds, including Dr. Onishi, a brilliant scientist. Optimus Prime, the leader of the Autobots has dispatched his troops to try to save Onishi and the others, enlisting the help of Koji, Onishi's son. But can these heroes outwit the evil Megatron, leader of the Predacons in time to save the Earth?

Only Koji and the Autobots can save the Earth from the evil Predacons! The Predacons have been battling the Autobots for thousands of years, but this time, they've kidnapped the world's greatest minds, including Dr. Onishi, a brilliant scientist. Optimus Prime, the leader of the Autobots has dispatched his troops to try to save Onishi and the others, enlisting the help of Koji, Onishi's son. But can these heroes outwit the evil Megatron, leader of the Predacons in time to save the Earth?

Professor Utonium and his son Ken are studying the strange Chemical X. When a mochi cake falls into the formula, it changes into Chemical Z. Ken fires a ray of Chemical Z at a glacier in Tokyo Bay, however that causes strange lights to scatter, some of them aim at three normal girls, Momoko, Miyako, and Kaoru. This gives them the power to transform into superheroes, the Powerpuff Girls Z!

Professor Utonium and his son Ken are studying the strange Chemical X. When a mochi cake falls into the formula, it changes into Chemical Z. Ken fires a ray of Chemical Z at a glacier in Tokyo Bay, however that causes strange lights to scatter, some of them aim at three normal girls, Momoko, Miyako, and Kaoru. This gives them the power to transform into superheroes, the Powerpuff Girls Z!