Jimmy Kilmartin's an ex-con who's trying to go straight. But he can't say no to a quick driving job because his so-called friend's life is threatened. The job is for Little Junior Brown, a violent and powerful villain. When things go wrong, Jimmy is left to do the time, and his whole life is turned upside-down, but if that wasn't enough, the cops won't leave Jimmy alone when he gets out... They want Little Junior Brown.

San Francisco police officer Frank Connor is in a frantic search for a compatible bone marrow donor for his gravely ill son. There's only one catch the potential donor is convicted multiple murderer Peter McCabe who sees a trip to the hospital as the perfect opportunity to get what he wants most: freedom. With McCabe's escape, the entire hospital becomes a battleground and Connor must pursue and, ironically, protect the deadly fugitive who is his son's only hope for survival.