Zane Ziminski is an astrophysicist who receives a message that seems to have extraterrestrial origins. Eerily soon after his discovery, Zane is fired. He then embarks on a search to determine the origins of the transmission that leads him into a Hitchcockian labyrinth of paranoia and intrigue.

In 1964, a brash, new pro boxer, fresh from his Olympic gold medal victory, explodes onto the scene: Cassius Clay. Bold and outspoken, he cuts an entirely new image for African Americans in sport with his proud public self-confidence and his unapologetic belief that he is the greatest boxer of all time. Yet at the top of his game, both Ali's personal and professional lives face the ultimate test.

Single mother Carla Moran is raped and attacked by an invisible force. She begins therapy with Dr. Phil Sneiderman, a psychiatrist who believes Carla's traumatic past is motivating her to commit self-induced injuries, rather than anything supernatural.

Like most of the people in her town, Karen Silkwood works at the local nuclear plant producing highly radioactive plutonium. Exposed one day to a lethal dose of radiation, Karen faces the blank walls of corporate indifference and denial. As her illness increases, her protest grows louder and she becomes an obvious danger to the powers that be.

Though she can spin wild tales of passionate romance, novelist Joan Wilder has no life of her own. Then one day adventure comes her way in the form of a mysterious package. It turns out that the parcel is the ransom she'll need to free her abducted sister, so Joan flies to South America to hand it over. But she gets on the wrong bus and winds up hopelessly stranded in the jungle.