Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

The well-known explorer and hunter Captain Spaulding has just returned from Africa, and is being welcomed home with a lavish party at the estate of influential society matron Mrs. Rittenhouse when a valuable painting goes missing. The intrepid Captain Spaulding attempts to solve the crime with the help of his silly secretary Horatio Jamison, while sparring with the anarchic Signor Emanuel Ravelli and his nutty sidekick The Professor.

In a 16th-century European town, the ruling family has been given a prophecy that, should there ever be twin boys born, the younger will murder the older; so is dismayed when twins are born to the popular baron. The older grows to be a selfish, slovenly man, who inherits the castle at his father's death and becomes ruler over the formerly happy villagers. He enjoys his power until he learns his younger brother is returning from abroad and, afraid of the prophecy, he determines to murder his sibling, hide his body in the "black room" - an old torture chamber sealed away behind the fireplace - and then impersonate him, right down to his withered arm. In this way he hopes to not only avoid the prophecy, but also escape consequences of his other criminal deeds and obtain marriage to a local girl of the nobility...

After being attacked and raped twice in one day, a timid, mute seamstress goes insane, takes to the streets of New York City after dark, and randomly shoots men with a .45 caliber pistol.

Lora Hart manages to land a job in a hospital as a trainee nurse. Upon completion of her training she goes to work as a night nurse for two small children who seem to be very sick, though something much more sinister is going on.

Rural runaway finds himself in Manhattan.