The girls in a high school literature club do a little icebreaker to get to know each other: answering the question, "What's one thing you want to do before you die?" One of the girls blurts out, "Sex." Little do they know, the whirlwind unleashed by that word pushes each of these girls, with different backgrounds and personalities, onto their own clumsy, funny, painful, and emotional paths toward adulthood.

After being in a coma for 17 years, Takafumi's middle-aged uncle suddenly wakes up speaking an unrecognizable language and wielding magical powers.

Ganta Nakami is a high school student who suffers from insomnia. He meets Isaki Magari, a girl with the same condition. A relationship forms as they share a secret and catch up on their sleep in their school’s abandoned observatory.