Sam and Phil embark on an international quest to prove once again they are The Wrong Mans.

Sam Pinkett and Phil Bourne, office workers for Berkshire County Council, have their menial existence turned upside-down by a chance phone-call and a case of mistaken identity. After being sole witness to a car crash on a desolate country road, Sam answers an abandoned mobile telephone and hears a message that was clearly not meant for him: "If you are not here by 5 o'clock, we will kill your wife". Encouraged by office mail-room delivery boy Phil that they can be the heroes of the hour, the duo soon find themselves plunged into a deadly kidnap situation.