The eminent Dr. Phibes awakens from a decade of suspended animation and heads to Egypt with the corpse of his dead wife, which he intends to resurrect by murdering people in strange and heinous ways.

Returning from Lapland, where he buried his father, a renowned scientist, Jerry Cornelius, comes back to London with the firm intention of taking revenge on his brother Frank and snatching his beloved sister Catherine from his clutches. Since the recent gigantic global conflagration, things have changed considerably. If he wanted to, Jerry could easily get hold of napalm to blow up Frank's hideout. But he prefers to join forces with the disturbing Mrs Brunner, who, with the help of three scientists – Smiles, Lucas and Powys – is trying to recover a mysterious microfilm left to Frank by his father...