Soon after a young woman breaks off her engagement to a doctor, the doctor is found murdered. Suspicion falls on his ex-fiancé and a pilot with a checkered past.

A pair of married ex-convicts trying to go straight get jobs at a department store. A gangster who knows about their past threatens to expose it unless they agree to help him rob the department store.

A gunfighter takes part in a scheme to bilk a wealthy cattle family out of half a million dollars by pretending to be their son, who was kidnapped as child.

Johnny's freeloading brother Henry will go to any length to bet on a tip at Belmont, including stealing from Junior's piggy bank. When Johnny's mother-in-law tells them to take Junior to the dentist to have a tooth pulled, and gives them $2 for the doctor, the game is afoot. The money goes to Henry's bookie, and the boys decide to pull Junior's tooth themselves... by tying a string onto the back bumper of a car. But a pet parrot spills the beans, and mother-in-law goes chasing after them with fire in her eye, and a fireplace poker under her coat.

A seemingly charitable soup kitchen operator (who moonlights as a criminology professor) uses his Bowery mission as a front for his criminal gang. Police attempt to close in on the gang as they commit a series of robberies, murders and bizarre experiments on corpses.