David Nau leads a band of modern day pirates who raid yachts and sail boats of people on vacation in the Caribbean. When reporter Blair Maynard and his son arrive to investigate the mystery of the disappearing boats, Nau and his band of raiders decide to induct them into their tribe.

Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.