This movie tells five stories set in a single day at the famed Chelsea Hotel in New York City, involving an ensemble cast of some 30-35 characters.

The death of a friend galvanizes three high school young women to reassess their friendship and their lives.

A mob enforcer is set up to take the fall for a multi-million dollar heist involving a rival gang boss. Merle (Eric Roberts) is a gambler stuck on a twenty-year losing streak, but his luck is about to change. Surviving a trap that was intended to kill him, Merle makes away with a beautiful woman and a piece of the take. Most men in that position would have been content to simply walk away with their lives, but Merle has been loyal for twenty years. Realizing he's been betrayed, something inside snaps. They used to call him "The Butcher" as a joke, but the laughter turns to screams when Merle returns to deliver the ultimate punchline.

Richard Clark has just left the well-known Wellington Academy to teach at Marion Barry High School. Now, he will try to inspire the D-average students into making good grades and try to woo a fellow teacher.

Detectives Jimmy and Paul, despite nine years as partners, can still sometimes seem like polar opposites—especially when Paul's unpredictable antics get them suspended without pay. Already strapped for cash and trying to pay for his daughter's wedding, Jimmy decides to sell a rare baseball card that's worth tens of thousands. Unfortunately, when the collector's shop is robbed and the card vanishes with the crook, Paul and Jimmy end up going rogue, tracking down the card and the drug ring behind its theft, all on their own time and without any backup—except for each other.

Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.

After Majestic gets burned to the ground, Nancy relocates her family to Ren Mar to set up shop and partners with Guilermo and his Boss, Esteban. Knowing she has nothing, Celia moves to Ren Mar to start over, but begins developing a surprising problem. Shane begins to embrace a dark side of himself. Silas and Doug decide to open up a medicinal marijuana store.

In 1981 New York City, a collection of twentysomethings try to cope with relationships, loneliness, desire and their individual neuroses on New Years Eve.

Three lovable party buds try to bail their friend out of jail. But just when the guys have mastered a plan, everything comes dangerously close to going up in smoke.