Georgina is a teacher determined to make a difference in the lives of the children she educates in the classroom of a wagon school in rural Mexico.

Julia is a mother, or rather, one of many mothers, sisters, daughters, colleagues, who have had their lives torn apart by the widespread violence in a country waging a war against its women. Julia is searching for Ger, her daughter. And in her search, she will weave through the stories and struggles of the different women she will meet.

After the death of her abusive husband, Matilde finds her new best friend in Miguel, her young, insecure, and disoriented neighbor.

After a ten year absence, El Chato returns to San Ignacio, his hometown, in order to retrieve a shipment of cocaine that was dropped there by a cartel pilot.