El Santo and his loyal friends will try to disarm a dangerous criminal organization.

Investigators Conrado and Fernando take a leave of the absence from the police force to track down Fernando's girlfriend Virginia. Virginia, a reporter, has left town and is working undercover as a barmaid in order to interview Refugio Canales, a criminal and small town municipal president. Conrado and Fernando soon call their friend Santo for help.

An aristocratic vampire swears an oath to kill the enemies who killed his father. In order to terrify them even further, he warns each one when he is coming for them.

The evil scientist Dr. Caronte plots to revive the brains of three dead scientists and use them to obtain the formula for the super-powerful neutron bomb. The resulting creation needs blood lots of blood, sending Caronte's midget assistant Nick and his legion of mutant monsters out to get fresh victims. However, the masked atom-superman Neutron vows to put a stop to Caronte's deeds.

A group of archaeologists break into the tomb of an ancient Aztec general, arousing the warrior's head and sending his undead servant out to take revenge on the careless scientists.

A wrestler tries to break up a covey of vampires, led by the King of Vampires.

A professor and a vampire hunter join forces to destroy the murderous vampire Nostradamus and his minions.

Tourists visiting the pyramids in Mexico experience a string of deaths and disappearances while staying at a nearby hotel. Police investigators Fernando and Cornado are assigned to the case and attempt to solve the mystery with the help of reporter (and girlfriend of Fernando) Veronica and the wrestler Santo.