A teacher in the middle of a messy divorce discovers that her husband has been recklessly dumping nuclear waste and wreaking havoc on the nearby wildlife. Now, she must contend with a feral, mutated rat in her home, and her soon-to-be ex who will do anything to keep his secrets.

A group of teenage, treasure seeking, grave robbers accidentally uncover the tomb of a satanic sect leader from the early Spanish colonial age, reawakening the diabolical killer, who promptly sets out to complete his unholy mission of spawning the son of Satan.