The 2010 show was recorded on 13 December and aired on 3 January 2011.
The teams were:
Wagner: Jonathan Ross and Ruth Jones
Posh & Specs: Michael McIntyre and Alan Carr
The Electric Moccasins: Richard Ayoade and Noel Fielding
Guest questions were provided by Nicole Scherzinger, Jack Black, Simon Pegg, Russell Brand, Seth Rogen, the cast of Misfits and Will Ferrell. The children of Mitchell Brook Primary School made their annual appearance acting out news stories, which included the Stig scandal and the Icelandic volcano eruption, as did Jon Snow with his fake news reports of popular songs. Lola, the cat put in a wheelie bin in August by Mary Bale appeared as a Mystery Guest. Louie Spence posed a question in the form of a dance routine representing the story of the trapped Chilean miners.
The final scores were:
Ross and Jones - 28
McIntyre and Carr - 25
Ayoade and Fielding - 12

Live from Studio Five was an early-evening British magazine programme which was produced by Sky News for Channel 5. It was presented by Kate Walsh and a line-up of other co-presenters during its run. It consisted of interviews and discussing topical issues, with an emphasis on showbusiness news and celebrity gossip, after originally covering stories from a popular news agenda. It aired its final edition on 4 February 2011 and was replaced by OK! TV in February 2011 which lasted just nine months on air before itself being axed.