The murder of the ex-wife of Doctor Sam Charney (Rutger Hauer) leads Detective Della Wilder (Pam Grier) to uncover a series of women's murders somehow linked to a big pharmaceutical company.

Stephen Glass is a staff writer for the respected current events and policy magazine The New Republic and a freelance feature writer for publications such as Rolling Stone, Harper's and George. By the mid-90s, Glass' articles had turned him into one of the most sought-after young journalists in Washington, but a bizarre chain of events - chronicled in Buzz Bissinger's September 1998 Vanity Fair article - suddenly stopped his career in its tracks.