TOKYO MER is formed by order from the Governor of Tokyo. The name of the group stands for TOKYO Mobile Emergency Room. The members are emergency care professionals and they are to go to sites of dangerous accidents and disasters by ER car. Their ER car is a large vehicle equipped with the latest medical devices and an operating area. There, TOKYO MER saves lives of the injured.

Kōta Kitami is a doctor for TOKYO MER and its leader. He holds a strong conviction that, regardless of the dangers, he will go to accident sites to save lives.

A young pathologist seeks answers to the mysterious death of a friend and soon comes into contact with the same cursed videotape that caused the death of the friend's wife and son, which is haunted by the curse of Sadako, a relentless spirit.

Junko Harumi was once a model student during her middle school and high school days. She failed to enter prestigious Tokyo University and her life has not gone smoothly since then. She has a hard time finding a job and having relationships with men. Now, at the age of 31, she works as a teacher at a private institute. 3 men, who vary in type, appear in front of her. Masashi Yakumo is smart and a cousin of Junko, Kyohei Yuri is a disorderly high school student and Kazuma Yamashita is Kyohei ’s teacher in high school.

A high school student steals the panties of a girl he likes but is witnessed, which sets off a chain of events that send his life and the lives of others around him out of control.

A government employee meets a hostess of a "pink club," and together they set out on a journey.

After four years overseas, Shozo returns to Japan to avenge his yakuza boss who was assassinated by his own treacherous top man, Kurawaki. The resulting battle leaves both men severely injured, and Shozo awakens in a mysterious medical facility to find his arm replaced with an M61 Vulcan cannon and his leg replaced with a rocket launcher. Meanwhile, Kurawaki has been fitted with mechanical augmentations of his own. Get ready for the second round.

After a childhood friend's suicide, Hideaki and his former classmates reunite to pay their respects. Soon after, a DVD, marked X arrives revealing a man being tortured, triggering a flashback in Hideaki, reminding him of witnessing a schoolmate being subjected to humiliating batsu (punishment) games. One evening, Hideaki is kidnapped and when he awakens the next day, he discovers he is in a recreation of his old school-room, along with his fellow classmates. Trapped and held captive by mysterious hooded figures, each of them must now play a brutally violent, version of the punishment game, in order to survive.