An orphan helps a doctor fight an epidemic in a small western town, in one of Allan Dwan’s closely observed studies in Americana.

A once-famous concert pianist has had her career ruined by her alcoholism. Her husband and a member of Alcoholics Anonymous try to help her recover.

Two different men are possessed by spirits of Native Americans after they separately wander into a sacred burial ground. When John and Sybil come home with their son after a trip to the Mojave Desert, they bring an unusual stone back as a memento of the trip. The stone seems to cause strange noises and other horrible inexplicable phenomena.

Uncle Remus draws upon his tales of Br'er Rabbit to help little Johnny deal with his confusion over his parents' separation as well as his new life on the plantation.