Three mental patients--a bad impersonator, a baseball player, and a gay fashion designer--escape their asylum and sexually assault their way into a girls' private school. The girls' education includes wrestling and karate, so the three madmen will find stern opposition they never expected.

When a Black doctor develops a serum that is supposed to regenerate dying liver cells and tests it on himself, it accidentally turns him into an albino monster with a lust for murdering prostitutes, pimps and drug dealers.