A deadly virus threatens to wipe out an entire Rocky Mountain town, leaving the town doctor to find some way to escape the soldiers who enforce the town's quarantine and devise an antidote. Matters take a more deadly turn after the physician is captured by a dangerously unstable band of militia extremists.

Firefighter Jesse Graves has to save ornithologist Jennifer and other people caught in a forest fire, which was set up by the lawyer of convicted killer Earl Shaye, who escaped from the prison with several of his inmates posing as firefighters to recover $37,000,000 in stashed loot.