A busload of travelers and their disgraced priest tour guide, on the hunt for Aztec ruins, decide to stop in a Mexican village on the eve of the Day of the Dead. Unbeknownst to them, a local doctor plans to begin a diabolical ritual intended to bring about Hell on Earth.

Framed by interviews with real life celebrities, Hollywood Mortuary tells the tale of a horror make-up artist who, in 1941 Hollywood, uses voodoo to resurrect two rival horror stars (thinly disguised versions of Karloff and Lugosi) from the dead to help revive his fading career.