In the sixteenth century, Francis Barnard travels to Spain to clarify the strange circumstances of his sister's death after she had married the son of a cruel Spanish Inquisitor.

When the residents of a luxury apartment complex outside Montreal are infiltrated by parasites and transformed into violent, sex-crazed maniacs, it's up to Dr. Roger St. Luc to contain the outbreak from spreading to the city.

Guido Anselmi, a film director, finds himself creatively barren at the peak of his career. Urged by his doctors to rest, Anselmi heads for a luxurious resort, but a sorry group gathers—his producer, staff, actors, wife, mistress, and relatives—each one begging him to get on with the show. In retreat from their dependency, he fantasizes about past women and dreams of his childhood.