After suffering terrible headaches and stomach cramps, Mr. Lăzărescu, a lonely 63 year-old man, calls for an ambulance, beginning one man’s hellish journey through Bucharest hospitals in search of proper medical care. As the night unfolds, his health starts to deteriorate fast.

The poet and journalist Ladima commits suicide and his friend, Fred Vasilescu, tries to find out the reasons of those actions. In his search he discovers a mysterious Miss T.

After his daughter is assaulted and left with an injury that may jeopardize her opportunity to study in the UK, a Romanian doctor decides to do whatever it takes to secure her future.

At the dinner table one night, a close-knit Romanian family is upset by a startling revelation.