Rome, summer 1943. Four children play war while the bombs of real war explode around them. Italo is the rich son of the Federal, Cosimo has his father in confinement and an atavistic hunger, Vanda is an orphan and a believer, Riccardo comes from a wealthy Jewish family. They are different but they don't know it and between them "the greatest friendship in the world" is born, impervious to the divisions of history that bloodies Europe. But on October 16 the Jewish boy is taken away by the Germans together with over a thousand people from the Ghetto. Thanks to Italo's father Federale, the three friends believe they know where he is and, to honor the "spit pact", decide to leave in secret to convince the Germans to free their friend. Yet another imaginative mission becomes reality, the three children travel alone in an Italy exhausted by war, among disbanded soldiers, deserters, occupying German troops, exhausted and hungry populations.

An italian version of the acclaimed and innovative Norwegian youth series Skam, which follows a group of teenagers in their everyday life of school, love and leisure time.

Stella is a clumsy, cynical, imaginative and tormented teenage girl. After a life-changing car accident involving a dog, she convinces herself she must count her age in dog years: one year of her life counts for seven, and now that she’s turning sixteen, she is a centennial. For this reason, Stella thinks she has not much time left to live and pens a bucket list of all the things she would like to achieve before she dies.

1275 a.C. - A young girl is imprisoned in the dungeons of an abbey where an alchemist uses her for his strange experiments. Only a young amanuensis will try to free her at any cost. 2011 a.C. - A couple of young teenagers, Cris and Jessy, go missing in the woods while a young woman comes out from the middle of nowhere. During the first investigations, the police find an odd manuscript from a tomb. Today - Leonardo, the Chief inspector of the Police department, is in charge of the investigation of the two teenagers disappearance. He's compelled to leave his video-testimony, because in the light of his last findings, he fears for his own life.

The first season centered around Eva Brighi, a teenage girl who struggles to trust her boyfriend, Giovanni. Eva eventually finds new friends in Eleonora, Federica, Sana, and Silvia, and focuses on herself for a change.

Season 2 broke from the traditional SKAM order of central characters by centering on Martino Rametta, a closeted gay teenager who quickly finds himself falling in love with Niccolò. Leaning on his friends Giovanni, Luca, and Elia, Martino begins to embrace who he truly is

Season 3 focused on Eleonora Sava. She lives with her older brother, completely independent from their parents, and prides herself on being wise beyond her years. However, her confidence threatens to come crashing down when she has to face her romantic feelings for Edoardo, a popular boy at school.

Season 4 focused on Sana Allagui, a Muslim-Italian girl. She begins to struggle to balance her faith and her friendships, as she begins to develop feelings for her brother's best friend, Malik.

Season 5 is the first to move past the original SKAM storylines, centering around Elia Santini. He struggles with toxic masculinity and sexual intimacy, as well as being forced to repeat his senior year of high school without his friends. Throughout the season, he finds himself drawn to classmate Viola.