American Steve Kendall, a freighter's radio officer, discovers seaman Carlson sending an unauthorized message ashore as the ship approaches his war-poised homeland. Carlson is shot in cold blood when he jumps ship and Kendall, implicated in the espionage, swims ashore to avoid arrest. A woman he meets at the dock hides him in her apartment, where he learns Carlson was her brother, and they both work in a sabotage ring. Nedra is a singer at Tio's Cafe, and she approaches Tio for help when both the saboteurs and the secret police try to capture Steve.

A New York City newspaper is sued for libel after reporting the wrong verdict in a murder trial.

A gang of mobsters try to take over the various moonshine operations in the hills of West Virginia.

George Sanders makes his final appearance as crook-turned-detective Simon Templar, a.k.a. "The Saint," in The Saint in Palm Springs. The gimmick in this one is a set of rare stamps, smuggled from England. Wendy Barrie is the true heir to this treasure, and the Saint is engaged to protect her and the stamps. Our hero meets Barrie in a posh Palm Springs resort, where a gang of homicidal thieves have converged to relieve the girl of her inheritance. Three murders and one kidnapping attempt later, the villains are foiled by the Saint, with the aid of his onetime partner in crime Pearly Gates (Paul Guilfoyle). The Saint in Palm Springs is the sixth in RKO's series of films based on the character created by Leslie Charteris.

Carmelita Fuentes is a fiery-Latin singer/dancer in Mexico City who has designs on Dennis Lindsay, an American publicity agent, for unclear reasons, while Lindsay's shiftless uncle Matthew Lindsay aids and abets her every step of the way to the marriage altar.

Two American leave a ship where they had stowed away, in a Middle Eastern port and wind up in the fighting in a brutal civil war