Mitch Robbins' 40th birthday begins quite well until he returns home and finds his brother Glen, the black sheep of the family, in his sofa. Nevertheless he is about to have a wonderful birthday-night with his wife when he discovers a treasure map of Curly by chance. Together with Phil and unfortunately Glen he tries to find the hidden gold of Curly's father in the desert of Arizona.

Kyle Fisher has one last night to celebrate life as a single man before marrying Laura, so he sets out to Vegas with four of his best buddies. But a drug and alcohol filled night on the town with a stripper who goes all the way, turns into a cold night in the desert with shovels when the stripper goes all the way into a body bag after dying in their bathroom. And that's just the first of the bodies to pile up before Kyle can walk down the aisle...

Three New York businessmen decide to take a "Wild West" vacation that turns out not to be the relaxing vacation they had envisioned.

FBI agent Barney Coopersmith is assigned to protect former Mafia figure turned informant Vincent Antonelli. In the witness protection program one is supposed to keep a low profile, but that is something that Antonelli has trouble doing. Coopersmith certainly has his hands full keeping Antonelli away from the Mafia hitmen who want to stop him testifying, not to mention the nightclubs...