While running from a drug deal gone bad, Mike Ross, a brilliant young college-dropout, slips into a job interview with one of New York City's best legal closers, Harvey Specter. Tired of cookie-cutter law school grads, Harvey takes a gamble by hiring Mike on the spot after he recognizes his raw talent and photographic memory.

A romantically challenged morning show producer is reluctantly embroiled in a series of outrageous tests by her chauvinistic correspondent to prove his theories on relationships and help her find love. His clever ploys, however, lead to an unexpected result.

A slacker and a career-driven woman accidentally conceive a child after a one-night stand. As they try to make the relationship work, they must navigate the challenges of parenthood and their differences in lifestyle and maturity.

Jenny Farrell is getting married. But how will her straight-laced family react when they find out that the woman they thought was their daughter’s roommate is actually her fiancée? As the old-fashioned Farrells attempt to come to terms with the prospect of a surprise daughter-in-law, they face a difficult choice: either adapt with the times or risk being left behind.

Barely coping with the end of her marriage, Tessa Connover learns that her ex-husband, David, is now happily engaged to Julia. Trying to settle into her new life after moving in with David, Julia believes she has finally met the man of her dreams, the man who can help her forget her troubled past. Soon, Tessa's jealousy starts to consume her, and she will stop at nothing to turn Julia's paradise into the ultimate nightmare.

When an elite assassin marries a beautiful computer whiz after a whirlwind romance, he gives up the gun and settles down with his new bride. That is, until he learns that someone from his past has put a contract out on his life.

Meredith Grey, the daughter of the once-renowned surgeon Ellis Grey, becomes an intern at the Seattle Grace Hospital. She meets fellow interns Cristina Yang, Isobel "Izzie" Stevens, George O'Malley and Alex Karev who become her closest friends during the intern program. She finds herself working with renowned surgeons such as the heart surgeon Preston Burke and Richard Webber, chief of surgery and old friend of her mother. She finds herself working under her one night stand and famous neurosurgeon Derek Shepherd and working with her resident Dr. Miranda Bailey also known as The Nazi.

The season continued to focus on the surgical residency of five young interns as they try to balance to the challenges of their competitive careers, with the difficulties that determine their personal lives. It was set in the fictional Seattle Grace Hospital, located in the city of Seattle, Washington. Whereas the first season put the emphasis mainly on the unexpected impact the surgical field has on the main characters, the second one provides a detailed perspective on the personal background of each character, focusing on the consequences that their decisions have on their careers. Throughout the season, new story lines were introduced, including the love triangle between Meredith Grey, Derek Shepherd, and Addison Montgomery, the main arc of the season. Also heavily developed was the story line involving Izzie Stevens' relationship with patient Denny Duquette, which resulted in critical acclaim and positive fan response.

For decades, childhood best friends Kate and Tully have weathered life's storms together -- until a betrayal threatens to break them apart for good.

The lives of several couples and singles in New York intertwine over the course of New Year's Eve.

Four friends start to receive morbid Valentine cards and realise they are being stalked by someone they had spurned 13 years ago. A masked killer is on the loose and Valentine's day is soon approaching.

A married man meets a beautiful woman in a Las Vegas casino and allows her to seduce him. When her jealous boyfriend finds them together, a scuffle results in the boyfriend's death. The lovers head to the desert to bury the corpse, but it disappears.

To the amusement of their adult children and friends, long-divorced couple Don and Ellie Griffin are forced to play the happy couple for the sake of their adopted son's wedding after his ultra conservative Catholic biological mother unexpectedly decides to fly halfway across the world to attend. With all of the wedding guests looking on, the Griffins are hilariously forced to confront their past, present and future - and hopefully avoid killing each other in the process.

Surly, a curmudgeon, independent squirrel is banished from his park and forced to survive in the city. Lucky for him, he stumbles on the one thing that may be able to save his life, and the rest of park community, as they gear up for winter - Maury's Nut Store.