Los Angeles, June 21st, 2028. While the streets are being torn apart by riots, the Nurse, who runs a clandestine hospital for criminals in the penthouse of the Artemis, a closed old hotel, has a rough night dealing with troublemaker clients: thieves, assassins, someone from the past and the one who owns the place and the whole city.

Former British soldier Jonathan Pine navigates the shadowy recesses of Whitehall and Washington where an unholy alliance operates between the intelligence community and the secret arms trade. To infiltrate the inner circle of lethal arms dealer Richard Onslow Roper, Pine must himself become a criminal.