Driven to desperation by his young and extravagant wife, alienist Dr. Emil Brandt has arranged a perfect crime; now he begs the police to lock him up before he can commit it.

Amidst a backdrop of growing violence and intimidation, independent cab drivers struggling against a consolidated juggernaut rally around hot-tempered Matt Nolan. Nolan is determined to keep competition alive on the streets, even if it means losing the woman he loves.

On the wharfs of San Francisco, saloon girl Toy, also known as Mary, lives over Mother Bright's bar. When Como Murphy, a fugitive from the law, hides in her room, she falls in love with him. He explains that after he spoke out about the rights of man to a crowd, a riot ensued, during which a policeman was killed. Como took the gun from the killer, but is thought to be guilty of the crime himself. Como, who reciprocates Mary's love, spends the night with her, but leaves to keep her out of danger. He joins the crew of a ship sailing to China after he is befriended by Turk, a big lumbering sailor who is also in love with Mary. Each man is unaware that they love the same woman.

Actress Jessica Wells, sister of actor Damon Wells, is on top of her form except when her husband Vance is around. When Vance takes her to the apartment of a theatrical producer she comes home incoherent and Vance is found dead in the vanished producer's hotel suite.

Among the travelers of varied backgrounds that meet and interact on one night at Union Depot, a metropolitan train station, are Chick and his friend Scrap Iron, both newly released from prison after serving time for vagrancy. Hungry and desperate for a break, Chick fortuitously comes across across a valise abandoned by a drunken traveler. In it he finds a shaving kit and a suit of clothes with a bankroll, which help transform the affable tramp into a dashing gent. After buying himself a meal, Chick seeks some female companionship among the many hustlers who walk the station. He propositions Ruth Collins, a stranded, out-of-work showgirl and takes her to the station's hotel.

Nightclub singer Joan Gordon runs away from her gangster boyfriend to become a mail-order bride to a struggling North Dakota farmer. Their relationship has a rocky start, but just as Joan realizes she's developing feelings for her husband, her old boyfriend arrives to win her back.