Brett Wade, gambler, gunslinger, and classical pianist, is wounded in a gunfight with the Ferris clan; the doctor finds signs of tuberculosis. En route to Colorado for his health, Brett stops in Socorro, New Mexico along with Ferris gunfighter Jimmy Rapp. Sheriff Couthen fears another shootout, but what Brett has in mind is saving waif-with-a-past Rannah Hayes from a life as one of Dick Braden's saloon girls.

A convicted racketeer becomes prison trustee when an inmate whom he persuaded to escape is killed.

After hearing that a famous actress is dying in a hospital after being hit by a car, a reporter goes to the hospital to interview the actress. She then tells the reporter that her wealthy fiance, who was killed in an accident several years before, was actually murdered. Before long the reporter finds herself in a web of corruption, mental illness and murder.

A former boxer turned taxi driver earns the scorn of his nagging wife and gets mixed up with jewel thieves.

After a wild night, wealthy Michael Reston's adulterous wife Charleen comes home with her dress in rags; murder results. Top New York defense lawyer J.G. Blane, whose own marriage exists in name only, arrives in Desert View, Nevada to find the townsfolk and politically powerful Sheriff Hoak distinctly hostile to the Restons. In due course, Blane discovers he's been "taken for a ride," and that quiet desert communities can be deadly.

Roger Quain, escorting two zoo-bound black panthers on the train from Milan to Paris, is unaware that a Western agent, Catherine Ullven, has hidden a microfilm in the collar of one of the animals. But when the train is derailed in the Swiss Alps and the panthers escape, she is forced to involve him in her mission, which now includes enemy agents hunting the microfilm, the animals, Catherine and Roger.

Grocery clerk Eddie Quaid, in danger of losing his father to alcoholism and his girl Julie through lack of career prospects, goes into boxing.

An ambitious coal miner is talked into becoming a boxer by his gambler brother.

Secret Service agents make a deal with a counterfeiting inmate to be released on early parole if he will help them recover some bogus moneymaking plates, but he plans to double-cross them.