The story follows General George Armstrong Custer's adventures from his West Point days to his death. He defies orders during the Civil War, trains the 7th Cavalry, appeases Chief Crazy Horse and later engages in bloody battle with the Sioux nation.

A nobleman searches for a hidden treasure in Guatemala.

Julia Garth, a female doctor, plans to introduce modern techniques of medicine to old Santa Fe in 1880, but is opposed by an established doctor, Rourke O'Brien.

The Florida Keys in 1840, where the implacable hurricanes of the Caribbean scream, where the salvagers of Key West, like the intrepid and beautiful Loxi Claiborne and her crew, reap, aboard frail schooners, the harvest of the wild wind, facing the shark teeth of the reefs to rescue the sailors and the cargo from the shipwrecks caused by the scavengers of the sea.