Radio personalities Larry Abbot and Vickie Pearle are stars of a mystery show. Since they announced their engagement, Larry has been plagued by speech problems and, seeking out an unconventional cure, he returns to his boyhood home, a mansion in the countryside, bringing Vickie along. Larry reunites with numerous family members, but discovers that there are sinister things afoot within the walls of the creepy estate.

When a happily married family man, who would never consider an affair, meets a beautiful woman in red, he is totally infatuated and desperate to make her acquaintance. However, as he tries out various schemes to sneak out to meet her, he realizes that adultery is not quite as easy as it looks.

After spending decades living in the shadow of his more famous and successful sibling, Consulting Detective Sigerson Holmes (Wilder) is called upon to help solve a crucial case that leads him on a hilarious trail of false identities, stolen documents, secret codes... and exposed backsides.