It has been a year since Matt Murdock retired from crime fighting as Daredevil. Wilson Fisk has been elected mayor of New York City after running on an anti-vigilante platform. The Kingpin may force Daredevil to come out of retirement.

该剧以主要讲述了芝加哥51号消防站应急救援队的故事。这一群英勇的消费队员们包括：副队长Kelly（泰勒·金尼 Taylor Kinney 饰）、队长Walter（伊默恩·沃克 Eamonn Walker 饰）、急救员Gabriella（莫妮卡·雷蒙德 Monica Raymund 饰），对自己的工作十分忠诚、资深消防员Christopher（David Eigenberg 饰）、玩命消防员Matthew（杰西·斯宾塞 Jesse Spencer 饰）、准消防员Peter（Charlie Barnett 饰）等。这群勇敢无惧的男女却义无反顾地冲进最危险的地方，每天都要和死神打交道，要在最紧张的时候做出最重要选择，每天都要面对自尊与自负的考验，工作的责任和压力给他们的性格带来了巨大影响......

A scientist becomes obsessed with returning his family to normalcy after a terrible accident.